What are the symptoms of G6PD deficiency?

Common symptoms of G6PD deficiency include pale skin, extreme tiredness, a fast heartbeat, rapid breathing or shortness of breath, yellowing of the skin and eyes (jaundice), and dark urine.

How common is G6PD deficiency?

G6PD deficiency is a relatively common genetic disorder. The risk of G6PD deficiency in children is influenced by the genetic background of both parents. In some populations, the prevalence of G6PD deficiency in newborns can be relatively high, whereas in others, it may be quite rare. Screening for G6PD deficiency is often performed in newborns, particularly in high-risk regions, to identify affected children early.

How is G6PD deficiency inherited?

G6PD deficiency is an X-linked genetic disorder, which means it is inherited in a manner that depends on a person's sex chromosomes. 

If a carrier female (heterozygous for G6PD deficiency) has children, there is a 50% chance of passing the G6PD deficiency allele to her offspring, regardless of the child's sex. Whether the child experiences symptoms depends on the presence of other factors and triggers.

How serious is G6PD deficiency?

The severity of G6PD deficiency can vary widely among individuals. The condition can be managed by avoiding triggers, maintaining a healthy lifestyle, and medical guidance to minimize the risks associated with this genetic disorder.